lauantai 16. helmikuuta 2013

Eteisvärinä aka flimmeri

-->
Atrial fibrillation, fibrillatio atriorum (AF)


Atrial fibrillation is the most common long lasting arrhythmia.
In atrial fibrillation the atria contract randomly and sometimes so fast that the heart muscle cannot relax properly between contractions. Electrical impulses move randomly to the ventricles and cause irregular and often rapid heart beat. This reduces the heart's efficiency and performance.
AF is rare with people under 60 years old, but it becomes general with age so that 10 per cent of people over 75 years old ail it.


Paroxysmal atrial fibrillation - this comes and goes and usually stops within 48 hours without any treatment.
Persistent atrial fibrillation - this lasts for longer than seven days (or less when it is treated).
Longstanding persistent atrial fibrillation - this usually lasts for longer than a year.
Permanent atrial fibrillation - this is present all the time and there are no more attempts to restore normal heart rhythm.


Symptoms                             

Symptoms can include palpitation, tiredness, shortness of breath, dizziness or feeling of fainting. However, some people only have mild symptoms, while other people have no symptoms at all.


Causes

Causes include high blood pressure, heart valve disease, hyperthyreosis and excess alcohol consumption. It is also associated with coronary heart disease. But in many patients no underlying cause can be found. Sometimes the AF can be resolved once the underlying condition has been dealt with.


Complications

AF can increase the risk of a blood clot forming inside the chambers of the heart, which can lead to a stroke. AF increases stroke risk by around four to five times.

                                 
Treatment

The treatment of atrial fibrillation (AF) is chosen individually for each patient taking into consideration the symptoms, co-existing illnesses, the risk factors of thromboembolic complications, the duration of the arrhythmia and the anticipated benefits and risks of the treatment.

1. Eliminating the factors that are exposing and triggering arrhythmias.
    Good treatment of basic diseases.
2.Rythm control
A. Rhythm transfer, restoration of sinus rhythm
  • cardioversion
  • rhythm transfer with medicine (flecainide, propafenone, vernakalant, amiodarone, ibutilide)
B. Upkeep of sinus rhythm
  • prophylactic medication (betablockers, calcium channel blockers, digoxin, amiodarone, dronedarone, flecainide, quinidine, propafenone, sotalol)
  • catheter ablation
  • surgical treatment
  • pacemaker treatment
3. Pulse rate control
  • medication (betablockers, calcium channel blockers, digoxin, amiodarone)
  • ablation of AV node and pacemaker treatment
4. Inhibition of thromboembolic complications
  • anticoagulation treatment (warfarin, ASA, dabigatran, rivaroxaban)

Factors supporting rate control

In elderly patients (> 65 years) with mild symptoms, it is justifiable to abandon repeated attempts at cardioversion  and concentrate on rate control and anticoagulation, particularly in the presence of presdiposing diseases, e.g. heart failure, coronary heart disease, hypertension or diabetes.

Other factors supporting rate control:
·      symptoms improve with rate controlling medication
·      rapid recurrence of AF (< 2–3 months) despite prophylactic medication
·      echocardiogram shows enlarged left atrium (> 5 cm)
·      the duration of AF > 6–12 months
·      a physically inactive patient
·      no contraindications to anticoagulation.


Factors supporting rhythm control

The restoration of sinus rhythm should be attempted, almost without exception in all cases, of first occurrence of symptomatic AF.
Rhythm control is the treatment approach of choice, despite the presence of co-existing diseases, if the patient has severe symptoms or haemodynamic complications despite maximal rate controlling medication
·      there is a good response to antiarrhythmic prophylactic medication
·      the left atrium is of normal size
·      the duration of AF is < 6 months
·      the patient is young and physically active
·      there are contraindications to anticoagulation.


References    

British Heart Foundation

Evidence-Based Medicine Guidelines

Käypä hoito. Eteisvärinä.
http://www.kaypahoito.fi/web/kh/suositukset/naytaartikkeli/.../hoi50036

Mustajoki & Ellonen 2012. Eteisvärinä (flimmeri). Lääkärikirja Duodecim.


Ei kommentteja:

Lähetä kommentti